What to Pair with NAD IV Therapy in Toronto: Top 6 IV Nutrient Add-Ons

POSTED BY TORONTO FUNCTIONAL MEDICINE CENTRE

If you’re getting NAD IV therapy from our Toronto clinic, have you thought about maximizing these sessions with added nutrients? 

In today’s world, patients are requesting preventative treatments to target healthy aging. This is due to the fact that chronic conditions are rising, which means a large portion of Canadians are struggling with their daily functioning and quality of life – boosting their morbidity and hospitalization risks. Oral and intravenous treatments containing NAD (nicotinamide adenine dinucleotide) have been embraced by some patients to help recover mitochondrial functioning, which can drop with age and elicit a cascade of symptoms. 

Taking NAD on its own may be beneficial for cellular energy, DNA repair, and mental clarity. But when NAD IV therapy is complemented with IV nutrients, you can further enrich detoxification, antioxidant levels, and bodily recovery. Think of it as a strategy to level-up your regime of NAD IV therapy! Below, we feature six nutrients that functional IV therapists may suggest combining with NAD+ IV drips

Top 6 IV Nutrients to Consider Adding to Your NAD+ IV Drip

    • Vitamin C: A high C IV drip may be valuable for managing cellular aging and immune-supporting protocols. As NAD has the potential to boost metabolic activity and cellular mechanisms, vitamin C might prevent oxidative stress from disrupting the healing process. Some IV therapy lounges offer NAD drips with extra boosts of high-dose vitamin C. Vitamin C drips can be administered before or after a NAD infusion to further address anti-aging concerns and cellular repair
    • Magnesium: Functional IV therapists might suggest IV magnesium as an add-on to help with sleep and stress. If you get nervous or have tight muscles during your NAD+ IV drip sessions, an add-on magnesium drip can be handy. This mineral is an essential cofactor for ATP production (also known as cellular energy production), with major roles in optimizing nerve and muscle functions. It’s also beneficial for relaxing muscles and reducing any cramping that might occur during or after intravenous treatments
    • Glutathione: Glutathione can complement NAD, especially If you’re struggling with excessive oxidative stress from poor detoxification. Glutathione – which is touted by scientists as a master antioxidant – can help neutralize free radicals, support liver detox pathways, and aid in cellular repair. When this nutrient is paired with NAD IV therapy, the order of the infusion process matters – IV glutathione may be given after a NAD drip is administered, which can help ‘mop up’ any oxidative byproducts. This relationship between glutathione and NAD may be beneficial for fast-tracking recovery, reducing inflammation, and supporting cellular functions. 
    • Alpha-Lipoic Acid (ALA): ALA is a fat- and water-soluble acid-based antioxidant that’s capable of regenerating other antioxidants. This nutrient supports mitochondrial function to aid with energy production, resilience, and possible anti-aging effects. Intravenous ALA may be prescribed by a functional IV clinician to help manage cognitive function and inflammation. However, ALA IV drips can come with medication interactions depending on your condition, but these can be discussed with your healthcare provider. 
    • Amino Acids and Taurine: Amino acids are the ‘building blocks’ of proteins that form neurotransmitters, detoxification enzymes, and immune function. The amino acid taurine may be specifically advised for calming the nervous system and supporting heart health; it also has osmoregulatory functions, meaning it can help your cells manage water balance. When paired with NAD IV, IV amino acids and taurine could be advantageous for accelerating muscle recovery from exercise, an illness, or surgery. Also, this IV combination may help ease withdrawal symptoms and stabilize mood for those being treated for substance overindulgences. 
    • B-Complex Vitamins: B vitamins are often depleted in the body under stress, illness, or hefty metabolic demands. These vitamins are foundational to energy metabolism, neurotransmitter synthesis, and detoxification; pairing them with NAD infusion therapy may be advised if you’re already deficient in B vitamins, as lacking B vitamins can disrupt NAD production in the body. Along with administering a NAD drip, some of these B’s may be advised for promoting key healthy functions: 
    • Vitamin B1: May further support mitochondrial functions, such as driving energy. 
    • Vitamin B5 (Pantothenic acid): Also essential for energy production, as well as synthesizing adrenal hormones and metabolizing carbohydrates. 
    • Folate: If poor methylation is suspected by your health practitioner, folate may be advised for improving chemical reactions in the body. 

Are you interested in complementing your next NAD+ IV drip with the nutrients listed above? Consulting with a functional medicine-practicing IV therapist is needed, as you require a prescription for customized IV nutrients. 

Why Consult with a Functional IV Therapy Provider

Realistically, we have different needs, genetic predispositions, medical histories, etc. – thus, some nutrients administered intravenously may or may not be suited for some individuals. Depending on your health condition, lab testing may be requested to modify your new intravenous dosages. Some functional IV Lounges, like ours, may request testing your current nutrient levels, especially for exploring underlying issues; in fact, measuring B vitamin, magnesium and antioxidant levels can help clinicians further tailor dosages to match your biology! 

Indeed, various IV nutrients can complement the effects of NAD infusions – the nutrients we listed may be supportive for metabolic, antioxidant, and nervous system pathways that NAD acts upon. And do keep in mind that working with a qualified healthcare provider, such as one from the Toronto Functional Medicine Centre, is necessary for personalizing intravenous treatments. 

Suggested reading: Exploring the perks of NAD IV Therapy in Toronto for Chronic Fatigue

Level-up Your Wellness with our Toronto Clinic 

At the Toronto Functional Medicine Centre, we focus on your biology to enhance mental clarity, athletic recovery, skin care, ATP production, and more. We adapt treatments to target your chief health goals, especially for managing chronic and autoimmune conditions. 

Our functional medicine and IV therapy clinic offer each patient a plethora of perks, including: 

    • Integrative health care, which means we encourage patients to mix and match treatment modalities. We can responsibly incorporate conventional medicine with hormone recovery programs, naturopathic medicine, homeopathy, botanical supplementation, psychotherapy, and more. 
    • Extended appointment times to thoroughly educate you about your conditions and treatments. Educational support can help you continue to make lifestyle decisions independently. 
    • Full access to our functional lab services, which are beneficial for scrutinizing oxidative stress, the gut microbiome, chronic inflammation, and nutrient and hormone levels. 

NAD infusion therapy is available in our IV Lounge, which is where we administer intravenous treatments. Our menu of IV drips and intramuscular injections includes vitamins A, B, C, D, E, glutathione, NAC, phosphatidylcholine, and more – these can be prescribed by our clinicians, and doses are customized with functional medicine principles. You can request your NAD+ IV drip to be administered as a stand-alone treatment or combined with other IV nutrients – it’s up to you! When intravenous treatments are combined with a healthy diet, exercise and functional medicine therapies, they can support optimal health. 

Give your cognitive function, energy levels and cellular repair a boost with key nutrients! Access to NAD IV therapy from the Toronto Functional Medicine Centre is simple – just start here to fill in our contact form and we’ll respond shortly. 

Disclaimer: The information in this article is designed for educational purposes only and is not intended to be a substitute for informed medical advice or care. This information should not be used to diagnose or treat any health problems or illnesses without consulting a doctor. You should always consult with a health care practitioner before relying on any information in this article or on this website. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of information you have read from the Toronto Functional Medicine Centre website or other affiliate media. 

 

References

Bouamama S, Merzouk H, Medjdoub A, Merzouk-Saidi A, Merzouk SA. Effects of exogenous vitamins A, C, and E and NADH supplementation on proliferation, cytokines release, and cell redox status of lymphocytes from healthy aged subjects. Appl Physiol Nutr Metab. 2017 Jun;42(6):579-587. doi: 10.1139/apnm-2016-0201. Epub 2017 Jan 23. PMID: 28177713.

“Key Findings from the Health of Canadians Report, 2024.” The Daily, Statistics Canada, 5 Mar. 2025, www150.statcan.gc.ca/n1/daily-quotidien/250305/dq250305a-eng.htm.

Martens, Christopher R., et al. “Chronic Nicotinamide Riboside Supplementation Is Well-tolerated and Elevates NAD+ in Healthy Middle-aged and Older Adults.” Nature Communications, vol. 9, no. 1, 2018, pp. 1-11, https://doi.org/10.1038/s41467-018-03421-7. Accessed 16 Sept. 2025.

Nguyen H, Pellegrini MV, Gupta V. Alpha-Lipoic Acid. [Updated 2024 Jan 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK564301/

Radenkovic D, Reason, Verdin E. Clinical Evidence for Targeting NAD Therapeutically. Pharmaceuticals (Basel). 2020 Sep 15;13(9):247. doi: 10.3390/ph13090247. PMID: 32942582; PMCID: PMC7558103.

Sharma, Arastu, et al. “Potential Synergistic Supplementation of NAD+ Promoting Compounds As a Strategy for Increasing Healthspan.” Nutrients, vol. 15, no. 2, 2023, p. 445, https://doi.org/10.3390/nu15020445. Accessed 15 Sept. 2025.

Superti, Fabiana, and Rosario Russo. “Alpha-Lipoic Acid: Biological Mechanisms and Health Benefits.” Antioxidants, vol. 13, no. 10, 2024, p. 1228, https://doi.org/10.3390/antiox13101228. Accessed 16 Sept. 2025.

Xie, Na, et al. “NAD+ Metabolism: Pathophysiologic Mechanisms and Therapeutic Potential.” Signal Transduction and Targeted Therapy, vol. 5, no. 1, 2020, pp. 1-37, https://doi.org/10.1038/s41392-020-00311-7. Accessed 16 Sept. 2025.

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