Category Archives: Nutritional IV Therapy

Why Visit An IV Therapy Toronto Clinic: 5 Benefits and Why We Do It

If you’re looking for a “helping hand” to address a health concern, visiting an IV therapy Toronto clinic may be of interest to you.

What exactly is IV therapy? Well, with IV therapy, swallowing an oral vitamin like a vitamin C supplement is not required. So here’s how IV therapy works: High doses of essential vitamins and minerals are delivered directly into the bloodstream via an IV infusion. This therapy bypasses the digestive system, which means digestive discomforts (i.e. diarrhea, stomach cramps, and nausea) are usually avoided.

Our clinic, the Toronto Functional Medicine Centre, is conveniently situated in Downtown Toronto and offers IV vitamin therapy to patients. In this blog post, we’ll discuss the benefits of IV vitamin drip treatments and why our clinic does it. Continue reading below:

Benefit 1 – Athletic Recovery

Hydration plays an important role in improving muscle recovery time for athletes. For example, triathletes and marathon runners need to maximize their hydration after exercising. IV therapy is a method for replacing fluids lost from physical activity and delivering minerals that the body needs for recovery.

It’s important to note, however, that IV drip treatments are not a substitute for proper rest and nutrition during periods of intense exercise. Hydration through an IV vitamin drip though may be helpful for recovery after a challenging workout session.

At the IV therapy Toronto clinic, Toronto Functional Medicine Centre, we offer the Pre- and Post-Exercise Amino Acid Drip IV. Not only does it help re-hydrate your body and replenish vital minerals for muscle recovery, it may also promote the cleansing of free radicals. Improved cognitive performance or cognitive health may also be a beneficial effect from this intravenous drip, as the treatment encourages optimal hydration.

Benefit 2 – Helps Alleviate Migraine Headaches

Migraine headaches can hinder a person’s quality of life. Research shows that increasing your intake of magnesium may help lessen the frequency and severity of migraines. That said, an IV therapy drip might be a safe avenue for providing your body with additional magnesium and other vitamins and minerals. As a result, recovery from migraines may show improvement from this treatment.

Additional benefits of increasing your magnesium intake may include: improved mood and stress management, reduced anxiety, improved quality of sleep, and diabetes management. For other complex health conditions, we recommend that you schedule an appointment with our naturopathic doctor to discuss your IV therapy needs.

Benefit 3: Helps Support Mood Disorders

Mood disorders, such as depression and anxiety, can be difficult to manage on your own. Many people who suffer from these mood disorders may be prescribed antidepressants and anti-anxiety medications from conventional medicine; but for some patients, adverse side effects may occur.

However, did you know though that low vitamin D levels might contribute to depression? Supplementing with vitamin D intramuscular shots may be an option to consider, especially if you suffer from gastrointestinal disorders. (Remember, IV therapy bypasses your digestive tract.) Support for your immune system, nervous system, bone health are also some of the health benefits of vitamin D booster shots.

Benefit 4: Detoxification

Free radicals are a natural by-product of our bodies’ metabolism. If the production exceeds elimination, free radicals can accumulate in cells and tissues, which can compromise your healing response, immune function and overall health. This may lead to cellular damage, illnesses or diseases.

Natural detoxification through an IV vitamin therapy is a process that helps flush the toxins out of your system. This may aid in cellular functioning and increasing wellness, while helping to handle other health conditions such as chronic fatigue syndrome, fibromyalgia, heavy metal toxicity, and autoimmune diseases, to mention a few.

Benefit 5: May Lessen Fatigue

Feeling tired and sluggish lately? Vitamin and mineral infusions may contribute to combating fatigue without making you feel edgy or fidgety. An intravenous therapy, such as the Energizer IV offered at our IV therapy Toronto clinic, may help with mild to moderate fatigue, severe sluggishness, malaise, and brain fog.

Also, did you know that oxidative stress might also cause fatigue? Toronto Functional Medicine Centre infuses antioxidants in vitamin IV therapy treatments to combat this and improve energy levels without the jittery side effects of stimulants, like caffeine.

Final Thoughts

As you’ve read, the benefits of IV drip therapy include optimal functioning, sports injury recovery, detoxification, improved energy, and other health highlights. If you’re seeking an alternative way to help reach optimal health or help manage current health conditions, do consider visiting your nearest vitamin IV therapy drip lounge.

Please note: for first-time patients at our clinic, an initial consultation and blood tests may be required prior to your first IV treatment. Keep in mind that we offer custom IV therapy to cater to your personal health goals! This may be an effective treatment for a wide range of various conditions, including an autoimmune disease, a thyroid condition, blood pressure concerns, inflammatory bowel disease, leaky gut syndrome, adrenal fatigue, and others. Custom IV drips may also help alleviate a viral infection. Nutrients such as amino acids, glutathione, antioxidants, high-dose vitamin C (ascorbic acid IV), and other minerals may be included in custom intravenous vitamin therapy at the Toronto Functional Medicine Centre. Every IV is blended with your health needs in mind.

Our IV therapy Toronto clinic is open Monday 11am–7pm, Tuesday 10am–5pm, Wednesday 9am–7pm, Thursday 9am–5pm, Friday 10am–7pm, and Saturday 9am–4pm. Let’s help naturally boost your body towards optimal functioning! Book your consultation by calling (416) 968-6961. Or contact us here to leave us a message.

Top 5 NAD+ Benefits for Brain Health and Restoration

nad+ benefits

NAD+ is among the indispensable molecules of life — yet it declines in the human body with aging.

If you haven’t heard of NAD+ or NAD+ therapy, now may be the time to learn about this treatment modality.

Nicotinamide adenine dinucleotide (NAD+) molecules are found in every cell in the body, including our brain cells. Although there are benefits to receiving NAD+ IV therapy or taking NAD+ supplements, health care practitioners and researchers are advocating NAD+ for helping restore brain function and promote brain health.

Benefits of NAD+ on the Brain

Research has shown that NAD+ influences the development, maintenance, and repair of energy at the cellular levels. Some of the benefits of NAD+ for brain health and restoration are:

1. Helps guard the nerve fibres from demyelination

NAD+ protects nerves against demyelination. It may sound like a big word, but demyelination means damage in the protective coating of nerve fibres. This protective covering, called the myelin sheath (hence the term “demyelination”), protects the nerve fibres in the brain, spinal cord, and specific nerves in the body. When the myelin is injured or somehow damaged, the nerve impulses (which are the signals to and from the brain) slow down or stop. In turn, this may cause muscle weakness and stiffness; loss of sensation, vision, and coordination; altered bowel and bladder function; and pain.

2. Acts as messengers in the body

Besides having a neuroprotective effect, NAD+ is essential in controlling physiological functions and cellular communication. NAD+ helps fine-tune the functioning of neurotransmitters, the chemicals that carry messages or signals from one area of the body to another. There are different types of neurotransmitters and some are involved in various functions, such as:

– Appetite
– Blood pressure control
– Digestive system’s response to food
– Liver function
– Memory
– Motivation
– Motor control
– Reward and reinforcement
– Regulation of the heart rate
– Sleep

3. Helps improve memory and maintain cognitive function

Neurotransmitters play a significant role in our central nervous system by supporting cognitive function. Ongoing research and clinical trials suggest that NAD+ may help improve memory and blood circulation in the brain of older adults with memory retention issues. This means that NAD+ may be beneficial in improving concentration and memory.

4. Helps fight against neurological diseases

Scientists believe that NAD+ therapy may help prevent brain diseases. These brain diseases include Parkinson’s disease and Alzheimer’s. Studies mention that low levels of brain cells energy (along with an unhealthy microbiome) may be responsible for the development and progression of these neurological diseases. By boosting NAD+ levels via supplementation and/or IV therapy, it may be possible to increase brain cells energy and vitality. Consequently, NAD+ therapy may help individuals stave off neurological disorders.

5. Contributes to restoring brain and neurological function

Whether you’re resting or engaged in intensive physical activity, your body consumes energy. NAD+ participates in the production of energy needed by most cells in the body. And one of the most energy-intensive organs in the body is the brain.

NAD+ is a naturally occurring molecule needed to convert glucose from the food that we consume into energy. When you have low levels of this molecule, there will be a low supply of brain sugar and, therefore, low amounts of energy for the brain cells to work properly.

How can NAD+ IV therapy help you?

Do you want to learn more about NAD+? At our Toronto clinic, we are passionate about helping patients with their integrative and functional medicine programs. You’re welcome to learn about our nutritional IV therapies, including vitamin B12, high-dose vitamin C and more. You may inquire about our NAD+ therapy, which may help rebuild neuroreceptor function and improve sleep, detoxification, and physical and mental longevity. Please call (416) 968-6961 or send us your message here.

 

References:

Fricker RA, Green EL, Jenkins SI, Griffin SM. The Influence of Nicotinamide on Health and Disease in the Central Nervous System. Int J Tryptophan Res. 2018 May 21;11:1178646918776658. doi: 10.1177/1178646918776658. PMID: 29844677; PMCID: PMC5966847.

Hong W, Mo F, Zhang Z, Huang M, Wei X. Nicotinamide Mononucleotide: A Promising Molecule for Therapy of Diverse Diseases by Targeting NAD+ Metabolism. Front Cell Dev Biol. 2020 Apr 28;8:246. doi: 10.3389/fcell.2020.00246. PMID: 32411700; PMCID: PMC7198709.

Lautrup, Sofie & Sinclair, David & Mattson, Mark & Fang, Evandro. (2019). NAD+ in Brain Aging and Neurodegenerative Disorders. Cell Metabolism. 30. 630-655. 10.1016/j.cmet.2019.09.001.

Mergenthaler P, Lindauer U, Dienel GA, Meisel A. Sugar for the brain: the role of glucose in physiological and pathological brain function. Trends Neurosci. 2013;36(10):587-597. doi:10.1016/j.tins.2013.07.001

Mehmel M, Jovanović N, Spitz U. Nicotinamide Riboside-The Current State of Research and Therapeutic Uses. Nutrients. 2020 May 31;12(6):1616. doi: 10.3390/nu12061616. PMID: 32486488; PMCID: PMC7352172.

NAD+ addition normalizes Alzheimer’s features. Yujun Hou, Sofie Lautrup, Stephanie Cordonnier, Yue Wang, Deborah L. Croteau, Eduardo Zavala, Yongqing Zhang, Kanako Moritoh, Jennifer F. O’Connell, Beverly A. Baptiste, Tinna V. Stevnsner, Mark P. Mattson, Vilhelm A. Bohr Proceedings of the National Academy of Sciences Feb 2018, 201718819; DOI: 10.1073/pnas.1718819115

Zachary M. Sheffler; Vamsi Reddy; Leela Sharath Pillarisetty. Physiology, Neurotransmitters StatPearls [Internet]. Last Update: May 21, 2020.

NAD+ IV Therapy for Lyme Symptoms: What is Nicotinamide Adenine Dinucleotide (NAD+)?

NAD+ intravenous (IV) therapy offers hope as a treatment for those with chronic conditions, including Lyme disease (Borrelia burgdorferi).

Lyme disease is a chronic disease that is transmitted to humans when infected black legged ticks (known as deer ticks) bite the skin and subsequently embed themselves.

Even after antibiotic treatments, people diagnosed with Lyme may continue to report debilitating symptoms such as joint pain, fatigue, weakness, brain fog, inflammation and neurological symptoms.

Nicotinamide Adenine Dinucleotide (NAD+) is a coenzyme found naturally in all the cells of the body and is integrated in various functions. It is a vitamin B3 (niacin) derivative that plays a vital role in energy production within the cells.

Studies have shown that NAD+ declines with age. As the natural aging process kicks in, the body fails to synthesize new NAD+ and the body may struggle to recycle NAD+ in the cells.

It is also believed that NAD+ levels decline in the presence of chronic diseases, including Lyme. Inflammation may result from chronic diseases because oxidative stress tends to increase in the body. However, research shows that intravenous NAD+ therapies or oral treatments of NAD+ precursors show promise in alleviating Lyme symptoms.

NAD+ IV therapy for Lyme symptoms

According to research from 2015, oxidative stress is suggested to be a potential result of the Lyme disease pathogen. Oxidative stress can trigger chronic inflammation symptoms because it elicits an immune system response to chronic pathogens (i.e. the bacteria that causes Lyme disease, Borrelia burgdorferi). Furthermore, oxidative damage ensues to proteins, DNA, and lipids, which have been linked to various chronic diseases (i.e. Lyme disease, chronic fatigue syndrome, cancer, Parkinson’s, Alzheimer’s and atherosclerosis).

During this particular 2015 study, a high build-up of mitochondrial superoxides – a free radical that contributes to oxidative stress – was found in those with Lyme when compared to the control group. This has led to the hypothesis that mitochondrial dysfunction takes place in Lyme disease and, therefore, NAD+ levels are depleted.

Today, many integrative functional medicine practitioners help restore NAD+ levels in Lyme patients intravenously to alleviate oxidative stress and help manage inflammation.

NAD+ mechanism of action: How does it help alleviate Lyme symptoms?

NAD+ IV therapy may benefit patients with Lyme disease in these ways:

  • NAD+ contributes to the formation of adenosine triphosphate (ATP), the unit in which we measure energy in the living cells.
  • Data suggests that NAD+ IV therapy may improve the cognitive function of individuals with chronic conditions, including Lyme disease.
  • NAD+ may help a person feel less tired; this may contribute to the overall well-being of the mitochondria, which are like tiny energy-producing factories in your cells. Scientists suggest that chronic diseases contain mitochondrial dysfunction in their physiopathology.

NAD+ IV therapy may improve your mood and cognitive functions by helping your brain create additional neurotransmitters.

Should you try NAD+ IV therapy to help treat Lyme symptoms?

Are you concerned that you’ve been exposed to infected black legged ticks? Or do you want to learn more about natural ways to alleviate Lyme symptoms?

At our Toronto-based clinic, we are available to help patients with integrative and functional medicine programs. Our NAD+ IV therapy program, a part of the integrative treatment approach for lyme disease, may help assist the body in restoring neuroreceptor function to an optimal level. This program may also promote improved sleep, detoxification, cell health replenishment and physical and mental longevity. Book your appointment today – click here to send us a message.

References

Barbosa JA, Sivaraman J, Li Y, et al. Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase. Proc Natl Acad Sci U S A. 2002;99(4):1859-1864. doi:10.1073/pnas.022476199

Fang EF, Lautrup S, Hou Y, et al. NAD+ in Aging: Molecular Mechanisms and Translational Implications. Trends Mol Med. 2017;23(10):899-916. doi:10.1016/j.molmed.2017.08.001

Massudi H, Grant R, Braidy N, Guest J, Farnsworth B, Guillemin GJ. Age-associated changes in oxidative stress and NAD+ metabolism in human tissue. PLoS One. 2012;7(7):e42357. doi:10.1371/journal.pone.0042357

Pall ML. Common etiology of posttraumatic stress disorder, fibromyalgia, chronic fatigue syndrome and multiple chemical sensitivity via elevated nitric oxide/peroxynitrite. Med Hypotheses. 2001;57(2):139-145. doi:10.1054/mehy.2001.1325

Peacock BN, Gherezghiher TB, Hilario JD, Kellermann GH. New insights into Lyme disease. Redox Biol. 2015;5:66-70. doi:10.1016/j.redox.2015.03.002

Pharmacy Compounding Committee Review: Nicotinamide Adenine Dinucleotide (NAD+)” viewed on September 3, 2020.

Pohanka M. Role of oxidative stress in infectious diseases. A review. Folia Microbiol (Praha). 2013;58(6):503-513. doi:10.1007/s12223-013-0239-5

Rajman L, Chwalek K, Sinclair DA. Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence. Cell Metab. 2018;27(3):529-547. doi:10.1016/j.cmet.2018.02.011

Zhu XH, Lu M, Lee BY, Ugurbil K, Chen W. In vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences. Proc Natl Acad Sci U S A. 2015;112(9):2876-2881. doi:10.1073/pnas.1417921112

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4 Surprising Things to Know About NAD+

nad iv therapy

What is NAD+?

Well, in order for our bodies to run smoothly, we need NAD+!

NAD+ is a coenzyme used in every biological process. It helps our enzymes create chemical reactions; it’s involved in regulating inflammation and metabolism, repairing DNA, detoxifying cells, regenerating mitochondria, and more.

As we age though, our NAD+ levels diminish; this may be concerning because we require NAD+ to support cellular health. Here are four things to know about NAD+ and how this coenzyme influences long-term health:

  1. NAD+ promotes restorative sleep.

Our circadian rhythm (sleep-wake cycle) relies on NAD+ to encourage the circadian rhythm to correspond with the cells’ mitochondria. In fact, NAD+ prompts the mitochondria to have our bodies use stored-up food as energy! But in order for this to happen, our circadian rhythm needs to be correctly working.

According to the journal Cell, “[t]he link of circadian genes and circadian regulation to health has been recognized in many disease-associated fields, including sleep disorders, diabetes, and cancer.” Because our circadian rhythm relies on NAD+ to trigger cell communication, low NAD+ levels may hinder the sleep-wake cycles and cause further health issues.

  1. NAD+ may facilitate in sustaining brain health.

Our memory may not be as sharp as we age; this may be due to a group of proteins called sirtuins. Sirtuins help keep us calm during stressful times; they normalize inflammation, guard our bodies from oxidative stress, and safeguard our DNA. Sirtuins require NAD+ to help turn some genes on or off (some of these genes are linked to aging-affiliated ailments, such as Alzheimer’s). When NAD+ levels are low, this prevents sirtuins from optimally working. More research on this protein family is underway, but it’s been proven that sirtuins need prime NAD+ levels to function properly.

  1. Binge drinking may lower your NAD+ levels.

According to the journal Experimental and Molecular Pathology, “NAD+ levels are markedly reduced when blood alcohol levels are high during binge drinking.”

When you excessively drink alcohol, your body may have difficulty with cells transforming food into energy. Low NAD+ levels from alcohol may prevent sirtuins from functioning; your sleep-wake cycle may get disturbed. Low NAD+ levels from binge drinking may also lead to cell cycle arrest, when cells cannot duplicate or divide; in turn, “DNA damage, mutations, apoptosis and tumorigenesis” may result writes Experimental and Molecular Pathology.

For those detoxing from binge drinking, health practitioners may suggest intravenous (IV) therapy. An IV drip that focuses on NAD+ may help replenish low NAD+ levels; this may encourage the cells to detoxify and repair, while helping to reduce withdrawal effects from alcohol.

  1. Boosting NAD+ levels may stretch your lifespan.

neurorecovery nad ivRemember, NAD+ levels decline as we age; low NAD+ levels may cause aging-related health concerns. Trends in Molecular Medicine has affirmed that neurodegenerative diseases, such as muscle atrophy, Parkinson’s, and cardiovascular diseases, all have the commonality of low NAD+ levels in the body.

But evidence has shown that when you increase your NAD+ levels, this may stall the development of age-related diseases. NAD+, explains the journal Skeletal Muscle, has a huge role “in skeletal muscle development, regeneration, aging, and disease. The vast majority of studies indicate that lower NAD+ levels are deleterious for muscle health and higher NAD+ levels augment muscle health.” 

For example, as we grow older, we want to stay limber. But our muscles may not bounce back from injuries due to “mitochondrial dysfunction,” writes Skeletal Muscle. It may be necessary to consider our NAD+ levels because “…NAD+ localization to mitochondria is important for muscle function,” further explains Skeletal Muscle. “Mitochondria are the subcellular compartments that have the highest level of NAD+ in skeletal muscle cells.” So when we boost NAD+ levels for anti-aging purposes, we are helping our cells regenerate mitochondria; in turn, this helps our bodies optimally function as we mature.

It should be noted that NAD+ plays a nutritional part, too. As per Skeletal Muscle, “Periods of muscle development and/or growth may be coordinated with nutrient availability. As NAD+ provides cells with information about nutrient levels, it is likely that NAD+ is involved in regulating these cellular transitions.” 

Do You Have Anymore Questions About NAD+?

With the arrival of a New Year, maybe your goal is to improve your anti-aging regime and lifestyle. IV therapy is one method for encouraging your body to increase NAD+ levels; in turn, this treatment may support improved sleep, detoxification, cell health replenishment and lengthen your physical and mental longevity.

At our clinic, we offer an integrative and functional medicine programs to our patients, including NAD+ IV therapy. The NAD+ IV therapy treatment was created to help assist the body in restoring neuroreceptor function to an optimal level, while helping to diminish cravings for addictive substances; the treatment may also assist in improving memory, mood and energy. To speak to our health care team about NAD+, click here.

References:

Chang, Hung-Chun, and Leonard Guarente. SIRT1 Mediates Central Circadian Control in the SCN by a Mechanism that Decays with Aging Cell 153, no. 7 (June 2013): 1448–60. https://doi.org/10.1016/j.cell.2013.05.027.

Fang, Evandro F., Sofie Lautrup, Yujun Hou, Tyler G. Demarest, Deborah L. Croteau, Mark P. Mattson, and Vilhelm A. Bohr. NAD thplus in Aging: Molecular Mechanisms and Translational Implications Trends in Molecular Medicine 23, no. 10 (October 2017): 899–916. https://doi.org/10.1016/j.molmed.2017.08.001.

Goody MF, Henry CA. A need for NAD+ in muscle development, homeostasis, and aging. Skelet Muscle. 2018;8(1):9. Published 2018 Mar 7. doi:10.1186/s13395-018-0154-1.

Imai, S., Guarente, L. It takes two to tango: NAD+ and sirtuins in aging/longevity control. npj Aging Mech Dis 2, 16017 (2016) doi:10.1038/npjamd.2016.17.

Samuel W. French, Chronic alcohol binging injures the liver and other organs by reducing NAD+ levels required for sirtuin's deacetylase activity, Experimental and Molecular Pathology, Volume 100, Issue 2, 2016, Pages 303-306, ISSN 0014-4800, https://doi.org/10.1016/j.yexmp.2016.02.004.

Yahyah Aman, Yumin Qiu, Jun Tao, Evandro F. Fang, Therapeutic potential of boosting NAD+ in aging and age-related diseases,Translational Medicine of Aging, Volume 2, 2018, Pages 30-37, ISSN 2468-5011, https://doi.org/10.1016/j.tma.2018.08.003.

IV Vitamin Therapies – Which Kind You May Need?

IV vitamin therapy comes in different types and is given to address specific health conditions. Before treatment starts, a thorough consultation is needed so you and your Naturopathic Doctor can work together on an ideal treatment program to help you achieve your health goals. Here are some popular intravenous vitamin drips offered at Toronto Functional Medicine Centre’s IV therapy Toronto clinic to help you decide which kind you may need.

Myers Cocktail

Myers cocktail is one of the popular intravenous treatments offered in our wellness center and in other IV drip lounges. Here’s an abstract from NCBI describing the origin of Myers IV:

“Building on the work of the late John Myers, MD, the author has used an intravenous vitamin-and-mineral formula for the treatment of a wide range of clinical conditions.”

Source: NCBI

People with adrenal fatigue may benefit from a Myers cocktail. It may be an effective energy booster and may help keep your body in balance.

High Dose Intravenous Vitamin C

There is more to vitamin C than just being considered a “vitamin”. High dose vitamin C has been shown to fight sepsis, a type of blood infection commonly seen in ICU patients.

“There’s a doctor in Virginia who is trying to promote IV mega-dose vitamin C for intensive care units (ICU) by lecturing to ICU doctors throughout the nation. Dr. Paul Marik was the head of the Norfolk General Hospital’s ICU.

In January of 2016, out of desperation, he decided to try IV mega-dose vitamin C on a middle-aged woman dying from septic shock in his unit.

His IV “cocktail” consisted of vitamin C, thiamine (vitamin B1), and hydrocortisone. Her turn-around and recovery were so unexpectedly rapid and complete that he continued using that cocktail for sepsis victims with a very high success rate.”

From: HealthImpactNews.Com

If you’re looking to get more information on high-dose IV vitamin C, contact us here.

Glutathione IV

Glutathione or “gluta” is quite popular among Asian countries as a whitening agent. But there is more to this iv treatment than its aesthetic effects. We published a blog post about Glutathione IV we highly recommend that you read: “3 Little Known Glutathione Benefits You May Never Have Heard Of”.

Immune Drip

If you find yourself constantly getting sick, this may be due to your weakened immune system. An intravenous vitamin drip that is designed to boost your immunity, may help speed up recovery, and fight and kill viruses, is what you may need.

For a free 15-minute introductory meeting about our iv therapies, you can call (416) 968-6961 or drop by our IV Toronto drip center at 162 Cumberland St 222 A, Toronto, ON M5R 1A8.

Recommended Reading: NAD IV Therapy – Everything You Need To Know About “The Crown Jewel of Detox”