Book An Appointment

tfmc-logo-darkblue

INTEGRATIVE FUNCTIONAL MEDICINE

A Toronto Functional Medicine Patient’s Guide to Magnesium Types

POSTED ON MARCH 22, 2022 BY TORONTO FUNCTIONAL MEDICINE CENTRE

At our functional medicine clinic in Toronto, our integrative care practitioners commonly suggest magnesium supplements to patients. This is because Magnesium is significant for improving wellness, especially at the cellular level.

But what is magnesium? Why is it necessary for reaching optimal health? Magnesium is a mineral needed for 300+ enzymatic responses in the body.  Compared to other minerals, magnesium is ranked number four as one of the copious minerals in the human body.

Unfortunately, magnesium deficiencies can lead to issues with metabolism, nutrition, and chronic conditions. “Emerging evidence confirms that nearly two-thirds of the population in the western world is not achieving the recommended daily allowance for magnesium, a deficiency problem contributing to various health conditions,” stated an article published in the journal Scientifica. With that said, a magnesium deficiency is something to prevent or alleviate through functional medicine.

Preventing and Treating Magnesium Deficiencies in Toronto

There are different types of magnesium supplements available; some are available topically, others are suitable as oral supplements. How do you know which one to choose? Based on recommendations from our functional medicine practitioners, here are some magnesium types to note:

Magnesium Type
What It Is
How It Works
Magnesium citrate

A mineral preparation with magnesium in salt form and citric acid; important for many body systems, especially the muscles and nerves; May be used as a laxative. 

May be used to release occasional constipation by causing water to be retained within the stools; helps with constipation symptom management by increasing the number of bowel movements and softening the stool so that it’s easy to pass.

Magnesium chloride Contains salt and chlorine with magnesium; chlorine is included to create a salt-like form.

May be an effective oral supplement because it swiftly absorbs into the digestive tract.

Integrative functional medicine doctors may use this form via intravenous applications to support depression and anxiety.

Magnesium glycinate Contains two glycine molecules per one magnesium molecule; due to the added synergistic calming effect of glycine, it may aid sleep, tight muscles and help provide anxiety relief. Glycine is already calming, so combining this and magnesium may provide further calming effects and enhance absorption. Magnesium glycinate can be used daily, as it does not have a laxative effect.
Magnesium oxide Contains ions from magnesium and oxygen; a common supplement you can purchase in Toronto. May have a low effect at increasing magnesium in the blood because it has a low rate of bioavailability; used clinically as a laxative.
Magnesium sulfate

Also known as epsom salt, this is a combination of magnesium and sulfate; may help treat constipation 

or for helping with pain management, muscle cramps and migraines.

Mainly used in a transdermal manner; can be dissolved in bathwater; may also be administered orally or via medically-supervised IV therapy.
Magnesium glycinate Contains two glycine molecules per one magnesium molecule; due to the added synergistic calming effect of glycine, it may aid sleep, tight muscles and help provide anxiety relief. Glycine is already calming, so combining this and magnesium may provide further calming effects and enhance absorption. Magnesium glycinate can be used daily, as it does not have a laxative effect.
Magnesium L-threonate A synthetic mix of magnesium and threonic acid; may help support cognition (i.e. age-related memory loss and depression) Animal studies have shown it effective at intensifying brain cell magnesium levels. Research has also shown that magnesium L-threonate “effectively crosses the blood-brain barrier to inhibit calcium flux in brain neurons,” reported an article in Neuron.
Magnesium taurate According to animal research, both magnesium and taurine may help with lowering blood pressure.

Normalizes electrical activity across membranes in heart and brain; stabilizes nerve cells; may provide a calming effect on muscles and nerve conduction.

Take note: further research is needed to confirm other benefits and effects of magnesium taurate.

Dietary Sources of Magnesium

A naturopathic functional medicine doctor would likely explain that magnesium is available via dietary means. Try these magnesium-rich foods in your meals:

  • Hemp seeds
  • Whole wheat bread
  • Kidney beans
  • Avocado
  • Broccoli
  • Cooked halibut
  • Raw carrots
  • Raisins

Not sure which foods are proper for your personalized medicine plan? Then please make an appointment at our center for functional medicine.

Contact Our Toronto Private Practice

How can magnesium upgrade your quality of life? Let’s help you discover the advantages of this mineral today.

Our integrative medicine approach consists of evidence-based functional medicine practices for virtual and in-person appointments. Our integrated patient care may help with these conditions: chronic diseases, chronic pain, pain management, men’s and women’s hormone imbalances, and infertility.

Our integrative treatment plans may include naturopathy, traditional Chinese medicine, western medicine (allopathic), cold laser therapy, medically-supervised IV therapy, acupuncture, understanding lifestyle influences, and functional medicine testing.

How can you naturally attain optimal health? Send us a note to reach our Toronto functional medicine practitioner for health advice. 

Disclaimer: The information in this article is designed for educational purposes only and is not intended to be a substitute for informed medical advice or care. This information should not be used to diagnose or treat any health problems or illnesses without consulting a health care provider. Consult with a health care practitioner before relying on any information in this article or on this website.

References:

Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, Rashidkhani B. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012;17(12):1161-1169.

Bagis et al. Is magnesium citrate treatment effective on pain, clinical parameters and functional status in patients with fibromyalgia? Rheumatol Int. 2013 Jan;33(1):167-72. doi: 10.1007/s00296-011-2334-8. Epub 2012 Jan 22.

​​Bigal, M. E., C. A. Bordini, et al. (2002). “Intravenous magnesium sulfate in the acute treatment of migraine without aura and migraine with aura. A randomized, double-blind, placebo-controlled study.” Cephalalgia 22(5): 345-53.

Coudray C, Rambeau M, Feillet-Coudray C, Gueux E, Tressol JC, Mazur A, Rayssiguier Y: Study of magnesium bioavailability from ten organic and inorganic Mg salts in Mg- depleted rats using a stable isotope approach. Magnes Res 2005;18:215–223.

Cox IM, Campbell MJ, Dowson D. Red blood cell magnesium and chronic fatigue syndrome. Lancet. 1991 Mar 30;337(8744):757-60

Fawcett W. J., Haxby E. J., Male D. A. Magnesium: physiology and pharmacology. British Journal of Anaesthesia. 1999;83(2):302–320. doi: 10.1093/bja/83.2.302.

Firoz M, Graber M. Bioavailability of US commercial magnesium preparations. Magnesium Research. 2001 Dec;14(4):257-262. PMID: 11794633.

Kim YS, Won YJ, Lim BG, Min TJ, Kim YH, Lee IO. Neuroprotective effects of magnesium L-threonate in a hypoxic zebrafish model. BMC Neurosci. 2020;21(1):29. Published 2020 Jun 26. doi:10.1186/s12868-020-00580-6

Kisters K. What is the correct magnesium supplement? Magnes Res. 2013 Jan-Feb;26(1):41-2. doi: 10.1684/mrh.2012.0326.

Lamontagne C, Sewell JA, Vaillancourt R, Kuhzarani C, (2012) Rapid Resolution of Chronic Back Pain with Magnesium Glycinate in a Pediatric Patient. J Pain Relief 1:101.

Lui et al. Efficacy and Safety of MMFS-01, a Synapse Density Enhancer, for Treating Cognitive Impairment in Older Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. Journal of Alzheimer’s Disease 49 (2016) 971–990 3.

Mauskop and Varughese. Why all migraine patients should be treated with magnesium. Neural Transm (Vienna). 2012 May;119(5):575-9.Chiu et al. Effects of McCarty MF. Complementary Vascular-Protective Actions of Magnesium and Taurine: A Rationale for Magnesium Taurate. Medical Hypotheses (1996) 46. 89-100

Nagle FJ, Balke B, Ganslen RV, Davis AW. The mitigation of physical fatigue with “Spartase”. FAA Office of Aviation Medicine Reports. Rep Civ Aeromed Res Inst US. 1963 Jul;26:1-10 2.

Intravenous and Oral Magnesium on Reducing Migraine: A Meta-analysis of Randomized Controlled Trials. Pain Physician. 2016 Jan;19(1):E97-112.

Ranade VV, Somberg JC.Bioavailability and pharmacokinetics of magnesium after administration of magnesium salts to humans. Am J Ther. 2001 Sep-Oct;8(5):345-57.

Rodríguez-Moran M, Guerrero-Romero F2. Oral magnesium supplementation improves the metabolic profile of metabolically obese, normal-weight individuals: a randomized double-blind placebo-controlled trial. Arch Med Res. 2014 Jul;45(5):388-93. doi: 10.1016/j.arcmed.2014.05.003. Epub 2014 May 13.

Gerry K. Schwalfenberg, Stephen J. Genuis, “The Importance of Magnesium in Clinical Healthcare”, Scientifica, vol. 2017, Article ID 4179326, 14 pages, 2017. https://doi.org/10.1155/2017/4179326

Shechter M. Reply to the letter: “what is the correct magnesium supplement?” by Kisters. Magnes Res. 2013 JanFeb;26(1):42-5. doi: 10.1684/mrh.2013.0335

Shechter et al. Comparison of magnesium status using X-ray dispersion analysis following magnesium oxide and magnesium citrate treatment of healthy subjects. Magnes Res. 2012 Mar 1;25(1):28-39. doi: 10.1684/mrh.2012.0305. 4.

Shin HJ, Na HS, Do SH. Magnesium and Pain. Nutrients. 2020;12(8):2184. Published 2020 Jul 23. doi:10.3390/nu12082184

Shrivastava P, Choudhary R, Nirmalkar U, et al. Magnesium taurate attenuates progression of hypertension and cardiotoxicity against cadmium chloride-induced hypertensive albino rats. J Tradit Complement Med. 2018;9(2):119-123. Published 2018 Jun 2. doi:10.1016/j.jtcme.2017.06.010

Schuchardt Philipp Jan, Hahn Andreas, “Intestinal Absorption and Factors Influencing Bioavailability of Magnesium- An Update”, Current Nutrition & Food Science 2017; 13(4) . https://doi.org/10.2174/1573401313666170427162740

Slutsky et al. Enhancement of Learning and Memory by Elevating Brain Magnesium. Neuron, 2010; 65 (2): 165 DOI: 10.1016/j.neuron.2009.12.026

Tarleton et al. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial. PLoS One. 2017 Jun 27;12(6):e0180067. doi: 10.1371/journal.pone.0180067. eCollection 2017.

Walker, Ann F. et al. “Mg citrate found more bioavailable than other Mg preparations in a randomised, double-blind study.” Magnesium research 16 3 (2003): 183-91.

Wang et al. Magnesium L-threonate prevents and restores memory deficits associated with neuropathic pain by inhibition of TNF-α. Pain Physician. 2013 Sep-Oct;16(5):E563-75.

BOOK AN APPOINTMENT

CALL US TODAY (416) 968-6961