Functional medicine treatments – including NAD IV therapy from our Toronto IV Lounge – can target your biological needs, such as managing metabolic health, fostering DNA repair, and more.

NAD (nicotinamide adenine dinucleotide) may be supplemented to promote positive effects for daily wellness. Studies have shown that this molecule innately decreases in the body as we age, which can have long-term effects on our neurological function, muscle health, and more. It’s earned the nickname “helper molecule” because it can attach itself to other molecules, triggering much-needed chemical reactions to occur for optimal functioning.

“Altered NAD+ homeostasis has been linked to multiple diseases affecting different organs, including the brain and nervous system, liver, heart and kidney,” confirms a Signal Transduction and Targeted Therapy article, which goes on to conclude that “…boosting NAD+ offers a promising option for enhancing [resilience] to aging or diseases, thereby extending a healthy lifespan.”

Some of our patients opt for NAD+ IV therapy to promote improved sleep; to support a “pep” in cognitive function; and to help boost energy levels. In addition to other health interventions (i.e. conventional medicine) and lifestyle changes, NAD IV therapy may encourage other beneficial effects – we list them below for educational purposes. 

Key NAD+ IV Health Benefits You Never Knew About

1. 1. May support weight loss: If you need to lose weight to manage a health condition or to improve athletic endeavors, IV NAD+ has been shown to help shed pounds. In a study of 30 individuals (over 45 years old) who were overweight/obese, it was shown that providing them with nicotinamide mononucleotide (NMN) – a precursor to NAD – “…significantly reduced total LDL and non-HDL cholesterol, body weight, and diastolic blood pressure,” an article from The Journal of Clinical Endocrinology & Metabolism reports. The participants consumed NMN tablets twice a day for 28 days. 
      
      
   2. Could contribute to extending the human lifespan: NAD is correlated with optimizing cellular function, DNA health, and immune cell vitality. Remember, NAD declines with age; thus, the functioning of our tissues may become impeded due to this deficiency, which is linked to several age-related conditions, including Alzheimer’s, obesity, and diabetes. Further research is needed, though scientists affirm that boosting NAD levels shows promise for elongating lifespan; this is because you’re replenishing these shortcomings. Physical and mental aging is rooted in mitochondrial dysfunction, and “…can be reversed by the increased levels of nicotinamide adenine dinucleotide (NAD+) in the body,” affirms a Journal of Advanced Research article. 
      
      
   3. Shown to promote anti-inflammatory effects that support both the functioning of the brain and gastrointestinal tract: NAD has demonstrated promising effects on both brain function and the GI tract. Regarding brain health, it’s been suggested that NAD supplementation may improve cognitive function and lower neuroinflammation seen in chronic cerebral hypoperfusion. Consequently, this relates to additional mitochondria protection and the lowered production of reactive oxygen species (ROS). NAD, therefore, may potentially be a valuable approach for handling cognitive impairments.
      
      Meanwhile in the gastrointestinal tract, NAD+ precursors have been identified as potential agents for promoting gut health and mitigating inflammatory bowel disease (IBD). Studies indicate that NAD deficiencies contribute to an unhealthy gut microbiome, leading to inflammation and dysbiosis. However, NAD supplementation shows promise in regulating inflammatory responses, immune function, and optimizing the gut barrier. By replenishing NAD levels, supplementation may prevent the initiation or progression of IBD, offering a potential avenue for therapeutic intervention. 

Suggested Reading: Top 5 FAQs On NAD IV Therapy From Our Toronto Lounge

Embark on a personalized treatment journey that includes NAD+ IV therapy – by exploring this, you may potentially unlock a wealth of benefits for your physical vitality and mental well-being. If you relate to the health concerns mentioned in this article, such as brain fog, memory loss, or cellular damage, we encourage you to consult with a healthcare practitioner at the Toronto Functional Medicine Centre (TFMC). 

How to Get IV NAD+ Therapy Drips from the TFMC

To get this drip treatment from us, follow our process to become a new patient:

• • Book your initial consultation in our clinic. During this appointment, we’ll discuss your wellness pursuits, while understanding your health history, genetics, lifestyle and environmental factors. This session is necessary to assess optimal IV ingredients for your needs and to tailor vitamin and NAD doses accordingly.
  • You then have the option of getting NAD+ IV by itself or with other nutrient-rich IV therapy drips immediately after your initial consultation; or you can book your IV administration for another day – in the end, it’s up to your comfort level!

Intravenous therapies are administered in our IV Lounge, which is located in our office. IV therapy treatments provide a complete absorption of nutrients, as they bypass the digestive tract and enter your bloodstream only. Sessions are supervised by our health team (naturopathic doctors and nurse practitioners). When combined with functional medicine treatments, regular oral supplements, and healthy lifestyle choices, NAD+ IV therapy can contribute to optimal health. Next to IV NAD-boosting molecules, we also offer folic acid, amino acids, vitamin C, magnesium, glutamic acid, vitamin A, vitamin E, and other natural ingredients compounded for intravenous therapies.

We have 50 + years of experience combined, and we’re proficient in tailoring various functional medicine treatments, such as allopathic medicine, herbal medicine, naturopathic medicine healing, acupuncture, IV vitamin infusions, holistic nutrition, hormone replacement therapies, and more. We can help treat brain fog, chronic stress, mineral deficiencies, excessive fatigue, and other symptoms, and help manage addiction relapse, mitochondrial function, heart disease, neurodegenerative diseases, oxidative stress, adrenal fatigue, and more.  

We believe in your potential to achieve optimal functioning – customize your treatment plan with our patient-centred approach to health care! NAD IV therapy from the Toronto Functional Medicine Centre is available NOW! Request your DISCOVERY session now by clicking here.

Disclaimer: The information in this article is designed for educational purposes only and is not intended to be a substitute for informed medical advice or care. This information should not be used to diagnose or treat any health problems or illnesses without consulting a doctor. You should always consult with a health care practitioner before relying on any information in this article or on this website. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of information you have read from the Toronto Functional Medicine Centre website or other affiliate media. 

 

References

Chen, C., Yan, W., Tao, M., & Fu, Y. (2023). NAD+ Metabolism and Immune Regulation: New Approaches to Inflammatory Bowel Disease Therapies. Antioxidants, 12(6), 1230. https://doi.org/10.3390/antiox12061230

Gibson, S. B., Mestayer, R., Berg, J., Grant, R., & Dyess, G. (2021). Intravenous Administration of Nicotinamide Adenine Dinucleotide Improves Cognitive Performance in Human Subjects: Implications for Clinical Populations. Archives of Physical Medicine and Rehabilitation, 102(10), e42. https://doi.org/10.1016/j.apmr.2021.07.585

Nadeeshani, H., Li, J., Ying, T., Zhang, B., & Lu, J. (2022). Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns. Journal of Advanced Research, 37, 267-278. https://doi.org/10.1016/j.jare.2021.08.003

Niño-Narvión J, Rojo-López MI, Martinez-Santos P, Rossell J, Ruiz-Alcaraz AJ, Alonso N, Ramos-Molina B, Mauricio D, Julve J. NAD+ Precursors and Intestinal Inflammation: Therapeutic Insights Involving Gut Microbiota. Nutrients. 2023 Jun 30;15(13):2992. doi: 10.3390/nu15132992. PMID: 37447318; PMCID: PMC10346866.

Okabe, K., Yaku, K., Tobe, K., & Nakagawa, T. (2019). Implications of altered NAD metabolism in metabolic disorders. Journal of Biomedical Science, 26. https://doi.org/10.1186/s12929-019-0527-8

Pencina KM, Valderrabano R, Wipper B, Orkaby AR, Reid KF, Storer T, Lin AP, Merugumala S, Wilson L, Latham N, Ghattas-Puylara C, Ozimek NE, Cheng M, Bhargava A, Memish-Beleva Y, Lawney B, Lavu S, Swain PM, Apte RS, Sinclair DA, Livingston D, Bhasin S. Nicotinamide Adenine Dinucleotide Augmentation in Overweight or Obese Middle-Aged and Older Adults: A Physiologic Study. J Clin Endocrinol Metab. 2023 Jul 14;108(8):1968-1980. doi: 10.1210/clinem/dgad027. PMID: 36740954.

Radenkovic, D., & Verdin, E. (2020). Clinical Evidence for Targeting NAD Therapeutically. Pharmaceuticals, 13(9). https://doi.org/10.3390/ph13090247

Ur Rahman S, Qadeer A, Wu Z. Role and Potential Mechanisms of Nicotinamide Mononucleotide in Aging. Aging Dis. 2023 Jul 27. doi: 10.14336/AD.2023.0519-1. Epub ahead of print. PMID: 37548938.

Xie, N., Zhang, L., Gao, W., Huang, C., Huber, P. E., Zhou, X., Li, C., Shen, G., & Zou, B. (2020). NAD+ metabolism: Pathophysiologic mechanisms and therapeutic potential. Signal Transduction and Targeted Therapy, 5(1), 1-37. https://doi.org/10.1038/s41392-020-00311-7

Yaku K, Okabe K, Nakagawa T. NAD metabolism: Implications in aging and longevity. Ageing Res Rev. 2018 Nov;47:1-17. doi: 10.1016/j.arr.2018.05.006. Epub 2018 Jun 5. PMID: 29883761.

Zhao, Y., Zhang, J., Zheng, Y. et al. NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway. J Neuroinflammation 18, 207 (2021). https://doi.org/10.1186/s12974-021-02250-8