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Top 3 Reasons to Consider NAD IV Therapy from Toronto

Top 3 Reasons to Consider NAD IV Therapy from Toronto


If you’re worried about forming poor mental clarity, age-related diseases, or cellular damage, NAD IV therapy from Toronto may promote some beneficial effects.  

At the Toronto Functional Medicine Centre (TFMC), we implement whole-body strategies to deal with the source of your health concerns. We recognize that physical ailments and mental health can feed off each other, stimulating a bodily imbalance. Depending on your needs, adjunct NAD IV therapy can offer unique health benefits for both your mind and body. For instance, it can potentially reduce oxidative stress that’s known to age your brain health and muscle function. IV NAD+ can also help lessen mitochondrial dysfunction, helping to strengthen cellular health and energy production for chemical reactions to happen, such as the conversion of food to energy.

Supplementing with this coenzyme can help revitalize your wellness safely and healthily. For educational purposes, we discuss why these IV therapy treatments may be taken for optimal health and functioning.   

Why Supplement with NAD (Nicotinamide Adenine Dinucleotide)

    • Your NAD levels may already be waning: The human body can create its own NAD. But, as the body ages, these coenzyme levels begin to drop. Scientists speculate that this may happen due to alterations to the body’s metabolic reactions and tissue structures. Some studies have also revealed that “By the time a mouse or human is middle aged, levels of NAD+ have fallen to half of youthful levels,” explains an article from Cell Metabolism. This NAD shortage can leave the body vulnerable to age-related weight gain, metabolic disease, memory loss, and weakened bone mass. 
    • NAD is naturally reduced when the body is inflamed: If you’re suffering from chronic inflammation, there’s a chance that NAD levels have already minimized. Researchers found that a boost in senescent cells or senescence – a state in which cells stop dividing and start harming other cells – degrades NAD by activating a protein called CD38. This protein is inside and outside cellular membranes and stimulates unwanted inflammation. It’s also important to note that alcohol overindulgence, chemotherapy, and obesity can also lower your current NAD levels. 
    • It may help elongate the human lifespan: As reported in an article by Aging Research Reviews, “… the upregulation of NAD metabolism, including dietary supplementation with NAD precursors, has been shown to prevent the decline of NAD and exhibits beneficial effects against aging and aging-associated diseases.” Due to the fact that waning NAD levels have been linked to degenerative diseases, poor cardiovascular health, cancers and inflammatory effects, it may have potential in sustaining optimal functioning into our senior years. 

So how can you boost these coenzyme levels with supplements? At the TFMC, our integrative care practitioners can help you with their patient-centred, individualized approach to health.  

Oral Supplements vs. Intravenous Therapy

As explained earlier, NAD is recommended based on your current health status. Tablets, capsules or sublingual treatments may be taken, and they’re usually in the form of precursors (i.e. nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR)). For optimal absorption, we can administer NAD via IV infusion therapy, which is also called intravenous therapy. 

IV therapy drips from our functional medicine clinic are designed to bypass the digestive tract. Instead, an IV tube is directed into your vein, which allows for a liquid formula to enter your bloodstream for immediate use. This treatment is suitable for patients with Crohn’s or colitis, as it assures of receiving a full absorption of nutrients without losing amounts to the digestive process. NAD IV therapy benefits vary between individuals, but may include an improvement in energy levels, mental health, sleep, metabolic functions (weight loss), and more. 

Note: Minor bruising and redness may appear on the injection site. NAD IV therapy side effects may potentially include some  fatigue, and mild cramping during administration. But these side effects  will  subside once your drip is finished , and your session is always supervised to ensure safety by our health team of naturopathic doctors, registered nurses and nurse practitioner. Let our health team know if you have any discomforts during your drip treatment.

Meet our TFMC health team

It can be frustrating feeling unheard when you experience new symptoms. We acknowledge this, which is why the TFMC tailors your treatment plan with an integrative approach to health care. 

We take ample time to educate patients on their health status, lab tests, and our functional medicine treatments; also, patients are welcome to collaborate as we customize their health strategies. This collective tactic inspires them to take control of their wellness, building confidence in applying lifestyle modifications. Treatments can be adapted for various health concerns, including mineral deficiencies, alcohol overindulgence, memory loss, dietary measures for heart disease, mitochondrial dysfunction, neurological function, athletic performance, and more. 

NAD IV therapy in Toronto brain health, for fertility, muscle function, and other health goals can be dosed for your biology. Your intravenous drip compound is never pre-mixed – each IV drip is freshly blended in our IV Lounge, which is where you can relax and focus on your needs with IV vitamin infusions. Your custom-made NAD+ IV drip may be administered as a stand-alone IV drip treatment or merged into a series of vitamin infusions. Ask us about our IV Lounge menu anytime – we carry vitamin C, folic acid, glutathione, vitamin B12 , amino acids with glutamic acid, vitamin E, plus targeted IV infusions (i.e. anti-aging IV drip). When you combine a regular NAD IV drip with daily healthy living and other functional medicine treatments (i.e. naturopathic medicine healing, Western medicine), optimal health may ensue. 

Unwrap your potential for optimal performance at home, in the workplace and gym – NAD can come with an array of health benefits! Request your consult for NAD IV therapy from the Toronto Functional Medicine Centre.

Disclaimer: The information in this article is designed for educational purposes only and is not intended to be a substitute for informed medical advice or care. This information should not be used to diagnose or treat any health problems or illnesses without consulting a doctor. You should always consult with a health care practitioner before relying on any information in this article or on this website. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of information you have read from the Toronto Functional Medicine Centre website or other affiliate media. 



Aquino-Martinez, R., Eckhardt, B. A., Rowsey, J. L., Fraser, D. G., Khosla, S., Farr, J. N., & Monroe, D. G. (2021). Senescent cells exacerbate chronic inflammation and contribute to periodontal disease progression in old mice. Journal of Periodontology, 92(10), 1483-1495.

Chronic inflammation causes a reduction in NAD+”, press release from the Buck Institute, released November 16, 2020, viewed on April 3, 2024. 

Covarrubias, A. J., Kale, A., Perrone, R., Alberto, J., Pisco, A. O., Kasler, H. G., Schmidt, M. S., Heckenbach, I., Kwok, R., Wiley, C. D., Wong, H., Gibbs, E., Iyer, S. S., Basisty, N., Wu, Q., Kim, I., Silva, E., Vitangcol, K., Shin, K., . . . Verdin, E. (2020). Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages. Nature Metabolism, 2(11), 1265-1283.

Kim, H., Ponte, F., Warren, A., Ring, R., Iyer, S., Han, L., & Almeida, M. (2021). A decrease in NAD+ contributes to the loss of osteoprogenitors and bone mass with aging. Npj Aging and Mechanisms of Disease, 7(1), 1-11.

Lasry, A., & Ben-Neriah, Y. (2015). Senescence-associated inflammatory responses: Aging and cancer perspectives. Trends in Immunology, 36(4), 217-228.

McElfresh KC, McDonald JF. The effect of alcohol stress on nicotinamide adenine dinucleotide (NAD+) levels in Drosophila. Biochem Genet. 1983 Apr;21(3-4):365-74. doi: 10.1007/BF00499145. PMID: 6407471.

McReynolds MR, Chellappa K, Baur JA. Age-related NAD+ decline. Exp Gerontol. 2020 Feb 22;134:110888. doi: 10.1016/j.exger.2020.110888. Epub ahead of print. PMID: 32097708; PMCID: PMC7442590.

Navas, L. E., & Carnero, A. (2021). NAD+ metabolism, stemness, the immune response, and cancer. Signal Transduction and Targeted Therapy, 6(1), 1-20.

Niño-Narvión, J., Rojo-López, M. I., Martinez-Santos, P., Rossell, J., Ruiz-Alcaraz, A. J., Alonso, N., Ramos-Molina, B., Mauricio, D., & Julve, J. (2023). NAD+ Precursors and Intestinal Inflammation: Therapeutic Insights Involving Gut Microbiota. Nutrients, 15(13).

Poljsak B, Milisav I. NAD+ as the Link Between Oxidative Stress, Inflammation, Caloric Restriction, Exercise, DNA Repair, Longevity, and Health Span. Rejuvenation Res. 2016 Oct;19(5):406-415. doi: 10.1089/rej.2015.1767. Epub 2016 Mar 16. PMID: 26725653.

Yaku K, Okabe K, Nakagawa T. NAD metabolism: Implications in aging and longevity. Ageing Res Rev. 2018 Nov;47:1-17. doi: 10.1016/j.arr.2018.05.006. Epub 2018 Jun 5. PMID: 29883761.


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