What is Sublingual Supplementation? A NAD IV Therapy Toronto Fact Sheet

POSTED BY TORONTO FUNCTIONAL MEDICINE CENTRE

Did you know that some nutrients can be taken sublingually? Our IV therapy Toronto Lounge can customize a NAD+ IV drip for you, or NAD can be absorbed under the tongue. 

And yes, you read that correctly – NAD can be administered under the tongue! This is how sublingual supplements are taken, and they provide rapid absorption into the bloodstream without swallowing tablets. In fact, vitamin D and vitamin B12 can be prepared as sublingual treatments. 

If you’ve been struggling with brain fog, low energy levels, and memory loss, this article may inspire you to finally address chronic symptoms. Our IV Lounge explains:

    • What exactly sublingual supplements are; 
    • The potential beneficial effects of sublingual and IV NAD+;
    • How to get access to NAD IV therapy from our functional medicine clinic. 

Understanding the sublingual route 

When something is called ‘sublingual’, it refers to inserting a supplement format – such as a lozenge – under the tongue. Taking supplements sublingually has the potential to promote quick onset for therapeutic purposes. This is because the space under the tongue holds blood vessels that allow for supplements to be swiftly absorbed into the bloodstream. This delivery route may offer beneficial effects for patients struggling with swallowing/digesting oral supplements, such as those with colitis, inflammatory bowel disease, etc. 

Keep in mind, there are differences between sublingual and regular oral supplements. Tablets and capsules are designed to be ingested, though there are times when the full dose cannot be absorbed by the digestive tract; this means you may not get the dose you originally intended. Just like eating food, supplements must travel through the digestive system. When tablets and capsules are broken down by enzymes, so does the nutritional dose; when this happens, you end up absorbing a dose that may be less than intended. 

If you want to take supplements sublingually, make sure these are designed for this purpose; inserting regular tablets under the tongue will not suffice, as sublingual lozenges require different ingredients. NAD sublingual supplements are available in our IV therapy Toronto Lounge, and these can be prescribed by our clinicians. 

What’s the deal with sublingual NAD treatments?

Nicotinamide adenine dinucleotide (NAD) is a crucial coenzyme that may support positive effects for degenerative diseases and the human lifespan. Taking this ‘helper molecule’ can help target aging symptoms, such as chronic pain, a fuzzy memory, a reduction in mental clarity, and slow tissue repair. 

Think of NAD as a powerhouse for mitochondrial function and energy production – every cell in your body contains NAD, and it has a key role in supporting cellular functions. But as people age, this essential coenzyme naturally declines in the body, hindering the repair of cells. This slash of NAD levels can leave you susceptible to chronic age-related health issues, such as those linked to cardiovascular health and metabolic diseases. 

Thus, sublingual NAD may be considered for supporting these health benefits: 

    • Improvement in energy levels: Cellular energy tends to decline with age. Taking NAD can aid in the mending of cellular functions, especially for augmenting daily energy levels. 
    • For supporting anti-aging health goals: NAD may help with targeting physical and mental discomforts linked to aging: “NAD+ plays a pivotal role in cellular metabolism and is a co-substrate for enzymes that play key roles in pathways that modify aging,” verifies a Plastic and Reconstructive Surgery article. 
    • Repairing muscle health for physical activities: Deficits of this vital coenzyme have been connected to skeletal muscle deterioration. However, NAD supplements could help with reformatting skeletal muscle on a cellular level. 
    • For recovering from substance/alcohol overindulgences: NAD “…can influence major signalling processes associated with the neurobiology of addiction,” says an Antioxidants article. As a result, supplementation could potentially lessen withdrawal symptoms and cravings. 

If you want to ensure that this coenzyme is topped up in your body, why not also try a NAD+ IV treatment? Like sublingual supplements, intravenous therapy allows for a quick absorption of nutrients without using the digestive tract. Learn how to get NAD+ IV therapy in the next section.  

How to get NAD IV therapy from our IV Lounge

NAD+ IV and sublingual supplements can be prescribed by our clinicians inside the Toronto Functional Medicine Centre. To get a prescription, please follow our procedure to become a new patient:

    • Book and attend your initial consultation. This session is mandatory for understanding your health concerns, allergies, underlying issues, and to determine your NAD dosage. 
    • After this consult, you are officially a new patient with us!

You can get your NAD+ IV drip immediately after your first consult, or have it administered another day – it’s up to you. You can also get a regular NAD IV drip or having it amalgamated into a sequence of intravenous drips. NAD therapy treatments (including sublingual supplements) are not meant to replace daily exercise, oral supplements, and healthy eating. These are for supportive purposes, and when they’re added to a nourishing lifestyle and other health interventions (i.e. conventional and naturopathic medicine), they can support optimal health improvements. 

IV Lounge sessions are supervised to ensure safety and comfort, and our health team includes naturopathic doctors, nurse practitioners and registered nurses. Along with NAD IV therapy, we offer plenty of intravenous ingredients, including vitamin C, several types of antioxidants, glutamic acid, mistletoe, amino acids, and more. Our IV drip ingredients are individually dosed with the principles of functional medicine – this means that each drip is uniquely calculated for your biological needs only! We look forward to meeting you in the near future. 

We’re scheduling consults for NAD IV therapy at the Toronto Functional Medicine Centre. Combine this IV drip with a healthy lifestyle and other functional medicine treatments to support cognitive function and tissue repair – call us now to book your initial visit

Disclaimer: The information in this article is designed for educational purposes only and is not intended to be a substitute for informed medical advice or care. This information should not be used to diagnose or treat any health problems or illnesses without consulting a doctor. You should always consult with a health care practitioner before relying on any information in this article or on this website. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of information you have read from the Toronto Functional Medicine Centre website or other affiliate media. 

 

References

Braidy N, Villalva MD, van Eeden S. Sobriety and Satiety: Is NAD+ the Answer? Antioxidants (Basel). 2020 May 14;9(5):425. doi: 10.3390/antiox9050425. PMID: 32423100; PMCID: PMC7278809.

Cantó C, Menzies KJ, Auwerx J. NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus. Cell Metab. 2015 Jul 7;22(1):31-53. doi: 10.1016/j.cmet.2015.05.023. Epub 2015 Jun 25. PMID: 26118927; PMCID: PMC4487780.

Conlon NJ. The Role of NAD+ in Regenerative Medicine. Plast Reconstr Surg. 2022 Oct 1;150(4 Suppl ):41S-48S. doi: 10.1097/PRS.0000000000009673. Epub 2021 Sep 28. PMID: 36170435; PMCID: PMC9512238.

Cuenoud, B., Ipek, Ö., Shevlyakova, M., Beaumont, M., Cunnane, S. C., Gruetter, R., & Xin, L. (2020). Brain NAD Is Associated With ATP Energy Production and Membrane Phospholipid Turnover in Humans. Frontiers in Aging Neuroscience, 12, 609517. https://doi.org/10.3389/fnagi.2020.609517

Hua, S. (2019). Advances in Nanoparticulate Drug Delivery Approaches for Sublingual and Buccal Administration. Frontiers in Pharmacology, 10, 1328. https://doi.org/10.3389/fphar.2019.01328

Ito, T. K., Sato, T., Takanashi, Y., Tamannaa, Z., Kitamoto, T., Odagiri, K., & Setou, M. (2021). A single oral supplementation of nicotinamide within the daily tolerable upper level increases blood NAD+ levels in healthy subjects. Translational Medicine of Aging, 5, 43-51. https://doi.org/10.1016/j.tma.2021.09.001

Xu, Y., & Xiao, W. (2023). NAD+: An old but promising therapeutic agent for skeletal muscle ageing. Ageing Research Reviews, 92, 102106. https://doi.org/10.1016/j.arr.2023.102106

BOOK AN APPOINTMENT

CALL US TODAY (416) 968-6961